Resources

Categories

Search
Categories
Product
Publication Type
Customer Support
Application
130 resources found

Publications

A high-plexity exome solution tailored for sensitive variant detection in single cells
AGBT-2021-Poster-Presentation-screenshot-2.png
Accurate detection of small genomic variants, copy number alterations, and heteroplasmy in early human embryos.
Accurate Genomic Variant Detection in Single Cells with Primary Template-Directed Amplification
Adaptation of MAS-Seq/PacBio and ONT long read technology to the ResolveOME™ multiomic workflow for single-cell transcript isoform and DNA amplicon interrogation

Victor J. Weigman

Analysis of DNA from brain tissue on stereo-EEG electrodes reveals mosaic epilepsy-related variants
Analysis of somatic mutations in 131 human brains reveals aging-associated hypermutability
Artificial intelligence-driven morphology-based enrichment of malignant cells from body fluid
Broadening the input application of ResolveDNA genomic amplification to detection of SNV in circulating DNA

Jon S. Zawistowski

Cell-type-resolved mosaicism reveals clonal dynamics of the human forebrain
Charting-and-deconvolution-of-microbial-diversity.png
Charting and deconvolution of microbial diversity by high-quality single-cell genomic reconstruction utilizing ResolveDNA Microbiome

Isai Salas González

co-delineating-genomic-thumb.png
Co-delineating genomic and transcriptomic modes of resistance to MEK inhibition in individual triple negative breast cancer cells

D.M. Arvapalli

combined-resolvedna-screen.png
Combined ResolveDNA® whole genome amplification with Twist Human Core Exome panel to generate high-quality human whole-exome data from single cells

Swetha D. Velivela

Comprehensive profiling of L1 retrotransposons in mouse
Comprehensive single-cell genome analysis at nucleotide resolution using the PTA Analysis Toolbox
Contrasting somatic mutation patterns in aging human neurons and oligodendrocytes
Deaminase-assisted single-molecule and single-cell chromatin fiber sequencing
Defining heritability, plasticity, and transition dynamics of cellular phenotypes in somatic evolution
Detecting somatic variants in purified brain DNA obtained from surgically implanted depth electrodes in epilepsy
Development and extensive sequencing of a broadly-consented Genome in a Bottle matched tumor-normal pair for somatic benchmarks
AGBT-2021-Poster-Presentation-screenshot-1 (1).png
Distinct resistance modalities to targeted kinase inhibition exposed by single-cell Primary Template-directed Amplification in acute myeloid leukemia and triple-negative breast cancer.
Diverse somatic genomic alterations in single neurons in chronic traumatic encephalopathy
eBook: Cell and Gene Therapies
Elucidation Of Tumor Clonal Diversity in An AML Drug Resistance Model Using A High Throughput Single Cell Genome Amplification Method

S. Velivela

Enrichment of viable cells from patient samples with LeviCell technology as input into the ResolveOME single cell multiomic workflow

Alison Rojas

Exome, IcWGS-based copy number assessment, complete transcriptome & surface protein expression from the same individual cell with ResolveOME™

Katherine A. Kennedy

exploring-drug-resistence-thumb.png
Exploring drug resistance mechanisms in different drug resistance models of an AML cell line using ResolveOME™ combined genomics and transcriptomics chemistry

S.D. Velivela

exploring-microbial-biodiversity-screen.png
Exploring microbial biodiversity through genome analysis using ResolveDNA Microbiome

Durga M. Arvapalli

extracellular-protein-thumb.png
Extracellular protein monitoring in the ResolveOMETM genomic and transcriptomic dual workflow to uncover cancer pathology mechanisms in single cells

T.V. Morozova

Genetic evolution of keratinocytes to cutaneous squamous cell carcinoma
Genome-Wide Disease Screening in Early Human Embryos with Primary Template-Directed Amplification
Genomic mosaicism reveals developmental organization of trunk neural crest-derived ganglia
going-beyond-the-atlas.png
Going beyond the atlas – mapping the tumor landscape with complete genomic signatures

Katherine Kennedy

High-fidelity, Large-scale Targeted Profiling of Microsatellites
High-Plexity, Single-Cell Exome Hybrid Capture of ResolveDNA® and ResolveOME™ Amplification Products
High-Plexity, Single-Cell Targeted Panel Hybrid Capture of ResolveDNA® and ResolveOME™ Amplification Products
High-Quality Nuclei Isolation from Postmortem Human Heart Muscle Tissues for Single-Cell Studies
High-resolution detection of copy number alterations in single cells with HiScanner
Identification of a mosaic MTOR variant in purified neuronal DNA in a patient with focal cortical dysplasia using a novel depth electrode harvesting technique
Improved detection of colibactin-induced mutations by genotoxic E. coli in organoids and colorectal cancer
AGBT-2021-Poster-Presentation-screenshot-3.png
Improving the sensitivity of detection of low frequency somatic variants via Primary Template-directed Amplification of single cells.
Integration of scHi-C and scRNA-seq data defines distinct 3D-regulated and biological-context dependent cell subpopulations
integration-of-the-resolveome-multiomics-workflow.jpg
Integration of the ResolveOME™ multi-omics workflow with IDT xGen™ hybridization capture at single-cell resolution to obtain high quality exome data

Durga M. Arvapalli

Inter- and intratumoral PIK3CA subclonal diversity in breast cancer contextualized by single-cell multiomics

Jon S. Zawistowski1

Measuring Longitudinal Genome-wide Clonal Evolution of Pediatric Acute Lymphoblastic Leukemia at Single-Cell Resolution
Molecular Effects of Indoor Tanning
Multiomic Single Cell Analysis of Primary Pancreatic Ductal Adenocarcinoma Enhanced by Fixation

Will Hwang

Pathogen dynamics and discovery of novel viruses and enzymes by deep nucleic acid sequencing of wastewater
Post-zygotic rescue of meiotic errors causes brain mosaicism and focal epilepsy
Precise exome analysis of blastocyst biopsy scale samples using primary template-directed amplification
Protocol for genome-wide analysis of somatic variants at single-cell resolution using primary template-directed DNA amplification
Quantitative and qualitative mutational impact of ionizing radiation on normal cells
Quantitative characterization of on-target and off-target variation induced by CRISPR+Cas9 systems at the single-cell resolution

Isai Salas-Gonzalez

Realtime morphological characterization and sorting of unlabeled viable cells using deep learning
Recurrent patterns of widespread neuronal genomic damage shared by major neurodegenerative disorders
scMicrobe PTA: near near complete genomes from single bacterial cells
Selective pressures of platinum compounds shape the evolution of therapy-related myeloid neoplasms
Single Day Workflow for High-Quality Whole Genome Analysis of Thousands of Single Cells with ResolveDNA

Jay A. West

single-cell-clarity-screen.png
Single-cell clarity and heterogeneity in copy number profiles in primary synovial & Ewing sarcoma with ResolveDNA™ genomic amplification

Katherine A. Kennedy

nature-genetics-thumb.png
Single-cell genome sequencing of human neurons identifies somatic point mutation and indel enrichment in regulatory elements
single-cell-identity-thumb.png
Single-cell identity and state coupled with genome-wide SNV and CNV in primary breast cancer with ResolveOME™ profiling

J.S. Zawistowski

Single-cell somatic copy number variants in brain using different amplification methods and reference genomes
Single-cell transcriptomic and genomic changes in the aging human brain
Somatic cancer driver mutations are enriched and associated with inflammatory states in Alzheimer’s disease microglia
somantic-genomic-changes-in-cingle-cell-thumb.png
Somatic genomic changes in single Alzheimer’s disease neurons
Somatic Mosaicism in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Reveals Widespread Degeneration from Focal Mutations
Somatic Mosaicism in PIK3CA Variant Correlates With Stereoelectroencephalography-Derived Electrophysiology
Somatic mutations distinguish melanocyte subpopulations in human skin
basejumper-research-platform-thumb.png
The BaseJumper™ research platform for single cell multiomic analysis & interactive visualization

V. Weigman

the-resolveome-platform-screen.png
The ResolveOME™ platform: integrated whole genome and whole transcriptome profiling from a single cell to unlock drug resistance mechanisms

Tatiana V. Morozova

Transient Differentiation-State Plasticity Occurs during Acute Lymphoblastic Leukemia Initiation
Trimodal Molecular Analysis in Single Cells of a Primary Breast Cancer Cohort with ResolveOME Amplification

Jon S. Zawistowski

unbiased-linkage-thumb.png
Unbiased linkage of SNV to expression in single cells for regulatory variant discovery influencing cancer drug resistance

I. Salas-González

poster_2.jpg
Unifying genomics and transcriptomics in single cells to illuminate cancer...
unifying-genomics-1.png
Unifying genomics and transcriptomics in single cells with ResolveOME™ amplification chemistry to illuminate oncogenic and drug resistance mechanisms
Unveiling Inter- and Intra-Tumor Heterogeneity in Ductal Carcinoma in Situ (DCIS) and Invasive Ductal Carcinoma (IDC) through Integration of Unified Single-Cell Copy Number and RNA Expression Data

Tia A. Tate

Validation of the first PGT-whole genome sequencing approach including mitochondrial variants
White Paper: CRISPR/Cas9 Gene Editing
White Paper: iPSC Therapies
White Paper: Viral Gene Therapies

Support

preimplantation-screenshot.png
A Fully Integrated Workflow Based on ResolveDNA® WGA for Complete Analysis of Human Embryos for Aneuploidy and Monogenic Disease (PGT-A + M)
thumb_poster.jpg
Accurate Single-cell Genomic Analysis Holds the Key to Understanding Cancer Heterogeneity
mosaicism-screenshot.jpg
Analysis of Somatic SNV and Indels in Single Neurons using ResolveDNA Whole Genome Amplification
Accurate-Single-cell-Entended-screenshot.jpg
Assessing the Heterogeneity of Single Cancer Cells using Primary Template directed Amplification (PTA)
BaseJumper Cloud End User License Agreement
basejumper-faqs.png
BaseJumper FAQs
BaseJumper Local End User License Agreement
basejumper-docs-thumb.png
BaseJumper® Docs
tile_protocols.jpg
Contact us for WGA, library preparation, and cell sorting protocols
resolvedna-microbiome-screenshot.jpg
Genomic Analysis of Single Bacteria using ResolveDNA® Microbiome
Integrated-Workflow-for-Spatial-Single-Cell-Genome-Analysis.jpg
Integrated Workflow for Spatial Single Cell Genome Analysis
integrated-workflows-for-single-cell-genome-analysis.png
Pairing Uniform Whole-Genome Amplification with Simple Single-cell Sorting
Resolve Training
resolveDNAscreen.jpg
ResolveDNA® in primary breast cancer
macbook-igv-mockup_small.png
ResolveDNA® Interactive Tech Note
lysis-screenshot.jpg
ResolveDNA® Lysis Optimization
tile_checklist.jpg
ResolveDNA® WGA Testing Checklist
ResolveOME™ and ResolveDNA® Data Preprocessing with Fastp Using the Cloud-based BaseJumper® Platform
resolveome.png
ResolveOME™: Comprehensive Multi-omic Single-Cell Analysis
single-cell-isolation-enrichment-screenshot.jpg
Single-cell Isolation and Enrichment

Videos

AACR 2023: A multiomic, single-cell lens on clonal evolution in breast cancer
AACR 2024: Adding Phenotypic Context to the Genomic Foundation with ResolveOME
AMP 2023: Discover Tumor Heterogeneity with Integrated Single-Cell Genomics and Transcriptomics
tile_pub1.jpg
ASHG: Primary Template-directed Amplification
basejumper-demo-thumb.png
BaseJumper® Demo
Webinar-Feb-28th.png
BioSkryb Genomics Webinar Single Cell Multiomic Analysis in AML
Breast Cancer Multiomics: Unified Insights in Tumor Heterogeneity
tile_balls.jpg
Discover the difference BioSkryb Genomics can make for you in WGA
tile_video2.jpg
Discover the “Why” behind BioSkryb Genomics
Enabling Rich Understanding of Gene-Edited Cells with Single-Cell Multiomics
Gene Editing: Past, Present, and Future
tile_vid3.jpg
Get to know BioSkryb first hand
tile_pub3.jpg
Harnessing Biotechnological Innovation for Pediatric Cancer
Leveraging single-cell whole genome sequencing to identify CRISPR/Cas9 gene editing on- and off-target events
BioSkryb-Resolve-cancer-heterogeneity-with-single-cell-resolution.jpg
Resolve cancer heterogeneity with single-cell resolution
resolveome-video-screenshot.jpg
ResolveOME™
tile_video3.jpg
SFAF: Studying Cellular Evolution with Primary Template-directed Amplification (PTA)
Somatic Mutations in Single-Cell Sequencing: Separating Signal from Noise
stanford_talk.jpg
Toward Personalized High-Resolution Leukemia Treatments Strategies using Single-Cell Genomics
Tracing the origin of pediatric leukemia using single-cell genome sequencing
Whole Genome Amplification: Studying Tissue Mosaicism and Evolution with Primary Template-Directed Amplification